Mild lanthanide(III) catalyzed formation of 4,5-diaminocyclopent-2-enones from 2-furaldehyde and secondary amines: a domino condensation/ring-opening/electrocyclization process.
نویسندگان
چکیده
Lewis acid catalyzed reaction of 2-furaldehyde and secondary amines results in the formation of 4,5-diaminocyclopent-2-enones exclusively as the trans diastereomers: computational studies support the stereochemistry of the adducts as arising from a thermal conrotatory pi4a electrocyclization of an initial ring-opened intermediate (a deprotonated Stenhouse salt).
منابع مشابه
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ورودعنوان ژورنال:
- Chemical communications
دوره 36 شماره
صفحات -
تاریخ انتشار 2007